ABSTRACT
Hansen's disease(HD) is a chronic infectious disorder acquired by inoculation of Mycobacterium leprae. With the establishment of complex multidrug therapy, the incidence rate of leprosy patients has continually shown to decline by 90% compared to the incidence rate in the 1990s. However, the prevalence of the disease still remains high in southeast asian countries. Due to the rarity and diverse nature of cutaneous presentation, HD is often misdiagnosed with other dermatoses or infectious conditions. Especially, when a patient presents with unusual presentation with leprosy reaction with no classical feature such as sensory disorders and skin lesion, the diagnosis is further delayed with misguided treatments. Herein we present a 27-year-old Indonesian immigrant who displayed clinical features mimicking that of orbital cellulitis who was later diagnosed with borderline lepromatous leprosy through histologic and PCR confirmation, in light of alerting the probability of leprosy in immigrants with intractable skin presentations.
Subject(s)
Adult , Humans , Asian People , Diagnosis , Emigrants and Immigrants , Incidence , Leprosy , Leprosy, Borderline , Leprosy, Multibacillary , Mycobacterium leprae , Orbit , Orbital Cellulitis , Polymerase Chain Reaction , Prevalence , Sensation Disorders , Skin , Skin DiseasesABSTRACT
Pyothorax-associated lymphoma is a distinct type of malignant lymphoma composed of lymphocytes, mostly of a B-cell nature. It occurs in patients with a long history of pyothorax and is strongly associated with Epstein-Barr virus infection. We experienced a case of pyothorax-associated lymphoma in a 66-year-old male. The patient had chronic pyothorax after tuberculous pleurisy was treated about 37 years earlier and was hospitalized for a recently occurring chest wall mass. A core needle biopsy of the chest wall mass led to a diagnosis of diffuse large B-cell lymphoma. Pyothorax-associated lymphoma is rare in Korea, but should be considered in patients with chronic pyothorax and a recently occurring pleural mass.
Subject(s)
Aged , Humans , Male , B-Lymphocytes , Biopsy, Large-Core Needle , Empyema , Empyema, Pleural , Herpesvirus 4, Human , Korea , Lymphocytes , Lymphoma , Lymphoma, B-Cell , Lymphoma, Primary Effusion , Thoracic Wall , Tuberculosis, PleuralABSTRACT
Pyothorax-associated lymphoma is a distinct type of malignant lymphoma composed of lymphocytes, mostly of a B-cell nature. It occurs in patients with a long history of pyothorax and is strongly associated with Epstein-Barr virus infection. We experienced a case of pyothorax-associated lymphoma in a 66-year-old male. The patient had chronic pyothorax after tuberculous pleurisy was treated about 37 years earlier and was hospitalized for a recently occurring chest wall mass. A core needle biopsy of the chest wall mass led to a diagnosis of diffuse large B-cell lymphoma. Pyothorax-associated lymphoma is rare in Korea, but should be considered in patients with chronic pyothorax and a recently occurring pleural mass.
Subject(s)
Aged , Humans , Male , B-Lymphocytes , Biopsy, Large-Core Needle , Empyema , Empyema, Pleural , Herpesvirus 4, Human , Korea , Lymphocytes , Lymphoma , Lymphoma, B-Cell , Lymphoma, Primary Effusion , Thoracic Wall , Tuberculosis, PleuralABSTRACT
Novel influenza A (H1N1) virus is a common pathogen of febrile respiratory infection recently. Here, we report the case of a 63-year-old male patient who presented with 3 days' ongoing cough and fever. He was diagnosed with novel influenza A (H1N1) pneumonia by real-time reverse-transcriptase-polymerase-chain-reaction (rRT-PCR). During treatment for novel influenza A (H1N1), his symptoms and radiologic findings improved initially, but multiple lung nodules developed subsequently and found on chest x-ray (on the 5th hospital day). Mycobacterium abscessus was isolated repeatedly from sputum and bronchoalveolar lavage fluid. To our knowledge, this is the first reported case of Mycobacterium abscessus lung disease in a patient with H1N1 influenza pneumonia.
Subject(s)
Humans , Male , Middle Aged , Bronchoalveolar Lavage Fluid , Cough , Fever , Influenza A Virus, H1N1 Subtype , Influenza, Human , Lung , Lung Diseases , Mycobacterium , Nontuberculous Mycobacteria , Pneumonia , Sputum , Thorax , VirusesABSTRACT
Novel influenza A (H1N1) virus is a common pathogen of febrile respiratory infection recently. Here, we report the case of a 63-year-old male patient who presented with 3 days' ongoing cough and fever. He was diagnosed with novel influenza A (H1N1) pneumonia by real-time reverse-transcriptase-polymerase-chain-reaction (rRT-PCR). During treatment for novel influenza A (H1N1), his symptoms and radiologic findings improved initially, but multiple lung nodules developed subsequently and found on chest x-ray (on the 5th hospital day). Mycobacterium abscessus was isolated repeatedly from sputum and bronchoalveolar lavage fluid. To our knowledge, this is the first reported case of Mycobacterium abscessus lung disease in a patient with H1N1 influenza pneumonia.
Subject(s)
Humans , Male , Middle Aged , Bronchoalveolar Lavage Fluid , Cough , Fever , Influenza A Virus, H1N1 Subtype , Influenza, Human , Lung , Lung Diseases , Mycobacterium , Nontuberculous Mycobacteria , Pneumonia , Sputum , Thorax , VirusesABSTRACT
Chromoendoscopy using Lugol's iodine solution is widely used to improve the detection of esophageal dysplasia or early squamous carcinoma. Although the solution helps to notice esophageal lesions and to delineate the lesions more clearly, it can cause mucosal irritation leading to retrosternal pain and epigastric discomfort infrequently. We report a case of acute gastric mucosal injury after application of Lugol's solution during chromoendoscopy in a 63-year-old woman.
Subject(s)
Female , Humans , Middle Aged , Carcinoma, Squamous Cell , Endoscopy , Iodides , Iodine , Mucous MembraneABSTRACT
Lymphoepithelial cysts of the oral cavity are rare lesions. The incidence when the number of lymphoepithelial cysts was compared to the total number of oral biopsies was 0.09 percent. Especially, the number of lymphoepithelial cysts originated from palatine tonsil was very small. They have been reported as branchial cleft cysts, branchiogenic cysts and pseudocysts because microscopically resemble each other. The lesions present as a small, well circumscribed, yellowish elevated nodule lined with stratified squamous epithelium surrounded by lymphoid tissue, usually on the floor of the mouth or the ventral or posterolateral surface of the tongue. Less frequent locations include the soft palate, mandibular vestibule, anterior pillar, and retromolar pad. We present a case report of a patient with an lymphoepithelial cyst in the right palatine tonsil presenting with throat discomfort.
Subject(s)
Humans , Biopsy , Branchioma , Epithelium , Incidence , Lymphoid Tissue , Mouth , Palate, Soft , Palatine Tonsil , Pharynx , TongueABSTRACT
Temporal bone fracture is usually the result of blunt head injury as ossicular disruption or isolated dislocation of individual ossicles may occur after temporal bone trauma. The incus is particularly prone to displacement because of its fragile ligamentous support. We report a rare case of incus dislocation into the external auditory canal associated with an underlying temporal bone fracture.
Subject(s)
Craniocerebral Trauma , Joint Dislocations , Ear Canal , Head Injuries, Closed , Head , Incus , Ligaments , Temporal BoneABSTRACT
BACKGROUND AND OBJECTIVES: Anatomical alterations of sinonasal cavity produced by various sinonasal diseases and surgeries can cause too much or too little sinus ventilation, which may develop pathology in the sinus. We studied the effect of the anatomical changes in nasal cavity and nasopharynx on the pressure of paranasal sinuses and ventilation of maxillary sinus in model experiment. MATERIALS AND METHOD: Anatomically accurate laboratory sinonasal model was constructed from computerized axial tomography scans of a healthy male. The pressure changes in the paranasal sinuses and oxygen washout from the maxillary sinus were investigated during controlled respiration by volunteer via corrugated tube connected to the nasopharynx of the normal model. The same procedures were performed in the adenoid hypertrophy and ethmoidectomized models. RESULTS: Adenoid hypertrophy caused an increase in maxillary antral pressure amplitude (the difference between peak positive and negative pressure), but showed a decrease in ventilation. In the ethmoidectomized model, ethmoidectomy improved maxillary sinus ventilation with slight decrease in the antral pressure amplitude, and widening of the ostium significantly increased ventilation, whereas near total middle turbinectomy impaired ventilation. CONCLUSION: The results obtained with the present model experiment may be of use for the understanding of the relations between anatomical change in the sinonasal cavity and sinus ventilation.
Subject(s)
Humans , Male , Adenoids , Hypertrophy , Maxillary Sinus , Nasal Cavity , Nasopharynx , Oxygen , Paranasal Sinuses , Pathology , Respiration , Ventilation , VolunteersABSTRACT
Osteoma is a slow-growing benign tumor composed of mature bone. Osteoma of the nose and paranasal sinuses is usually asymptomatic and most commonly occurs in the frontal sinus, followed by the ethmoidal and maxillary sinus. The occurrence in the sphenoidal sinus and nasal cavity is very rare. We present a case report of a patient with an isolated osteoma in the right nasal cavity presenting with nasal obstruction.